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Co-Prevalence Of Typhoid And Malaria Fever Among Patient Attending Medical Center

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ABSTRACT

Prevalence of malaria and typhoid fever in patient attending Shehu Muhammad Kangiwa medical centre Kaduna. Polytechnic. Where investigated to determine the level of infection. A total number of 25 blood samples were collected and analyzed for the presence of malaria parasite test using microscopy and widal serelogical test using widal kit for the presence of salmonella antigens

 

Content

Title Page

Declaration

Approval Page

Dedication

Acknowledgment

Table of content

Abstract

CHAPTER ONE

1.0     Introduction

Scope and justification 3

Aim and objectives 4

CHAPTER TWO

2.0     Literature review

2.1     Life cycle of Anoplele Mosquito

2.2     Epidemiology of Malaria and Typoid  Fever

2.3     Pathogensis (Typhoid)

2.4     Pathogensis (Malaria)

2.5     Transmission

2.6     Clinical Features of Malaria and Typhoid Fever

2.7     Laboratory Diagnosis

2.7.1  Treatment of Malaria and Typhoid Fever

2.7.2  Prevention and Control of Malaria and Typhoid Fever

CHAPTER THREE    

MATERIAL AND METHODS

3.0     Collection of Sample

3.1     Widal Test

3.2     Widal Slide Test Procedure

CHAPTER FOUR

Result 19

CHAPTER FIVE

DISCUSSION, CONCLUSION AND RECOMMENDATION

5.1     Discussion

5.2     Conclusion

5.3     Recommendation

References

 

CHAPTER ONE

1.0 INTRODUCTION

Malaria is a mosquito borne infections disease of human and other animals caused by parasitic protozon of the genus plasmondium. commonly the disease is transmitted via a bite from an infected female anopheles mosquito, which introduced the organism from it’s saliva into a person’s circulatory system in the blood, the protiosts travels to the liver to manure and reproduce.

malaria is characterizes by shivering and periodic fever followed by headache, muscular and joint points, vomiting, rise in temperature up to 41oC,  convulsion (in children) and in severe cases coma and death (Elevier, 1993; Kakkilaya, 2000).

malaria in humans is caused by four species of plasmodium parasites namely, P. Falciparum, P. Vivaz, P.ovale, P, malariae. The fifth is the zoonotic species plasmodium known as P. knowlesi which is prevalent in south east Asia, causes severs malaria  but also cause severe infections in humans. The vast majority of death are caused by P.Falciparum and P. vivax, While P. Ovale and P. malaria cause a milder form of malaria that is rarely fatal (WHO, 2005).

Malaria is transmitted from man to man by the female anopheles mosquito, one of the most capable vectors of human diseases. untreated malaria can be fatal and can lead to death. Drugs such as artermether have been in use for the treatment of malaria (Hall, 2000).

Typhoid fever is an  illness caused by the bacterium of the gram negative known as salmonella typhi. it is very commonly world wide and can be carried in the human bloods stream and intestinal tract. It is transmitted by food or water contaminated with the bacteria from an infected person or sewage containing the bacteria after multiplying in the body of the infected person. symptoms includes high fever, high temperature from 3905 to 400C, weakness, headache, lack of appétit and abdominal. pains (Rowe 1990).

Typhoid fever is an important infectious disease and considered as a global disease and health problem since longtime. it is said that Alexandra, the great died from complication of typhoid because of the last description of his final illness from royal diaries is consistent with diagnosis of typhoid fever, though, relevance data is lacking (Wan, 1997). World health organization has estimated that approximately, seventeen million cases and six hindered thousand annual death occur each year worldwide due to typhoid (Wain, 1997).

A study quoted that typhoid fever incidence is very high in south east Asia (>100 cases per 100,000 per years). in endemic areas prevalence of bacteria in febrile infacts is an high as 2.3%. Typhoid fever has great social and economic burden in developing countered because of hospitalization, its complications, income less e.t.c (Wan, 1997).

Most common age of reportedin iess 3-19years in endemic areas, but typhoid has been reported in less 3years of age in india and Bangladesh (WHO, 1991). a gram negative bacterium. it is estimatimated that this organism is about 50,000years old (Roww, 1990).

Malaria and typhoid fever remain diseases of major public health importance in the tropics, causing significant mobility and mortality (Ryan and Ray 2004). malaria and typhoid fever are commonly associated with poverty and may also be a major hindrance to economic development (carabollo, 2014).

SCOPE AND JUSTIFICATION

Typhoid and malaria co-infection is a major public health problem in many developing countries. of the co-infection treated are  base on method of diagnosis plagued with assumptions which possibly exaggerate the situation, because of high occurrence of malaria and typhoid in Nigeria co-infection are common. Both causes significant mobility, mortality and economic loss this research work is limited to determining the coprevelance of typhoid and malaria among patients attending Shehu Mohammad Kangiwa Medical centre, Kaduna Polytechnic, Tudun wada Kaduna.

AIM AND OBJECTIVES

To determine the prevalence of malaria parasite and typhoid fever among patients attending Shehu Mohammad Kangiwa Medical centre, Kaduna Polytechnic, Tudun wada Kaduna.

To determine the prevalence of malaria and typhoid fever in relation to age and sex.

To determine the Co-infection rate of malaria and typhoid fever among the ferbrile patients attending Shehu Mohammad Kangiwa Medical centre, Kaduna Polytechnic, Tudun wada Kaduna.

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